2015 was another successful year for NHMRC project grants, with 2 projects awarded funding in a highly competitive round. Funding was awarded for investigation of the mechanism of action of the novel triazine antimalarials, through a Project Grant led by Jonathan Baell (MIPS) in collaboration with the Avery (Griffith), Edstein (AAMI) and Ralph (Unimelb) labs. The other grant was led by Natalie Trevaskis (MIPS), which will use metabolomics approaches to investigate lymph-adipose interactions. We will also participate in another successful project grant led by Mike Inouye (Unimelb), using systems biology approaches to understand host-pathogen interactions involved in Typhoid disease.